Study of formulation and FTIR Analysis of Aloe Vera Gel for Periodontal Disease Therapy

Santi Chismirina


Numerous antibacterial chemicals found in Aloe vera, including tannins and flavonoids, have been used in therapeutic formulations due to their antibacterial properties. Gel-based medication preparations are easy to administer and quickly absorb in dentistry, particularly for the periodontal tissue. The purpose of this study is to identify a gel formulation containing 10% Aloe vera as a potential gel for the treatment of periodontal disease. The identification of Aloe vera was the first step, which was then followed by an extraction procedure utilizing the maceration method with 70% ethanol as a solvent. FTIR and phytochemistry analyses were performed on the obtained extract. The 10% Aloe vera gel formulation and testing phase comes next. This involves checking the gel's homogeneity, spreadability, viscosity, organoleptics, pH, storage stability, and adhesion. The results show that Aloe vera gel is brown in color, semi-solid, homogenous, and has an adhesive power of 3.16 seconds. Its spreadability ranges from 5.06 to 5.2 cm, and its viscosity is 3123 cps. At room temperature and cold, the gel does not split. These findings indicate that Aloe vera gel satisfies the test parameter criteria as a gel, is stable in storage, and includes antibacterial components such as anthraquinones and phenolics.


Aloe vera; gel; periodontal tissue; acemannan; herbal plant

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